Can i take misoprostol 12 hours after mifepristone

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How soon after taking mifepristone can you take misoprostol?

You will need to take misoprostol 36–48 hours after taking mifepristone. The usual dose is 800 micrograms (4 tablets) of misoprostol. Misoprostol must be taken bucally. This means you must keep each tablet between the cheek and gum for 30 minutes before swallowing any remaining fragments with water.

Which time is best for a patient to take misoprostol?

Misoprostol is best taken with or after meals and at bedtime, unless otherwise directed by your doctor. To help prevent loose stools, diarrhea, and abdominal cramping, always take this medicine with food or milk. Do not give this medicine to another person.

How long should I wait between doses of misoprostol?

The impact of repeat doses of misoprostol is not clear (ACOG, 2009). The ACOG states that one repeat dose may be administered no earlier than 3 h after the first dose and typically within 7 days, if there is no response to the first dose (ACOG, 2015).

Do you have to wait 24 hours after taking mifepristone?

you decide to take the medication home with you and continue the treatment there, you will be given a box of six tablets. You will be advised by the nursing staff to take these 24 to 48 hours after taking the mifepristone tablet in clinic.

How many misoprostol should I take after mifepristone?

A recent meta-analysis also found that mifepristone–misoprostol regimens with at least two misoprostol doses may achieve higher efficacy and decreased rates of incomplete and continuing pregnancy for gestations up to 56 days.

Can I take misoprostol and mifepristone at the same time?

After taking mifepristone, your doctor should direct you to wait 24 to 48 hours before taking another medication (misoprostol) by mouth as a single dose. The medications may not work as well if you take misoprostol sooner than 24 hours after taking mifepristone or later than 48 hours after taking mifepristone.

Can I insert 2 misoprostol?

The recommended dose of misoprostol is 800 mcgs (4 2

How many tablets of misoprostol should be taken a day?

Dosage is based on your medical condition and response to therapy. If you are taking this drug to prevent stomach ulcers, take it by mouth usually four times a day, after meals and at bedtime to minimize diarrhea, or as directed by your doctor.

Which method is best for taking misoprostol?

Conclusion: Administration of misoprostol by the sublingual route is better than the oral and vaginal routes for cervical ripening.

Can we take misoprostol after 24 hours?

You will take the misoprostol pills at home on Day 2 or 3 (24—48 hours after taking the mifepristone at the clinic). Take the anti-nausea pills, if we gave them to you, and pain pills to prevent cramps.

When should mifepristone be repeated?

Abstract. The recommended time interval between mifepristone and misoprostol in medical second trimester termination of pregnancy (TOP) has been 36–48 h. However, a more flexible interval would be of value.

Can misoprostol work after 48 hours?

Research most strongly supports using misoprostol between 24-48 hours after the Mifepristone. Misoprostol also works when it is used earlier or later, and using it late is much more effective than not using it at all.

How long does mifepristone stay in your system?

Following a distribution phase, elimination of mifepristone is slow at first (50% eliminated between 12 and 72 hours) and then becomes more rapid with a terminal elimination half-life of 18 hours.